Chiral HPLC/SFC columns

The Lux line of polysaccharide-based columns is suitable for the identification and resolution of enantiomers. Lux columns are offered with two chiral stationary phases (CSPs), both of which use coated derivatised cellulose as the chiral selector. The two phases combine to create a dependable screening set with a wide range of selectivity. The Lux line is based on chiral technology that Phenomenex acquired along with the company Sepaserve.

Lux Cellulose-1 uses cellulose tris (3, 5-dimethylphenylcarbamate) as the chiral selector.

LuxCellulos-2 introduces a new chiral selector, cellulose tris (3-chloro-4-methylphenylcarbamate), providing a stationary phase. This column offers complementary selectivity to Lux Cellulose-1. These two phases combine to create a dependable screening set with a wide range of selectivity. Lux columns are offered in 3 and 5 µm particle sizes, packed for analytical-scale use or AXIA-packed for preparative applications.

Enantiomers of chiral compounds may have different pharmacological effects in biological systems. The demand for chiral separations is on the rise with FDA mandates that enantiomers of all chiral drugs (in development) must be screened separately on their pharmacodynamic and pharmacokinetic properties.

Other applications include toxicology, flavour analysis, and chemical and pesticide analysis.