PerkinElmer QSight LC/MS/MS system for complex samples

Thursday, 29 October, 2020 | Supplied by: PerkinElmer Pty Ltd

When it comes to analysing complex samples like food, cannabis and biological matrices, it is important to have the right system that can help to comply with regulations and detection limits. PerkinElmer’s QSight LC/MS/MS system, with the QSight LX50 UHPLC, has been designed to provide the capability and confidence required to analyse the most challenging samples, all in a compact, easy-to-use design.

One of the major challenges in food safety testing is pesticide residue screening, which requires a combination of LC and GC analysis. This relies on multiple sample extraction procedures and analytical methods, which directly impacts sample turnover and costs. The dual-source configuration (ESI/APCI) of the QSight LC/MS/MS system provides true multiplexity. Laboratories can maximise the output from a single injection with the two complementary ionisation modes and transfer the analysis of GC amendable pesticides on a single LC/MS/MS platform.

Matrix complexity is another common challenge faced by many laboratories, affecting analyte response and instrument performance over time. Sample clean-up and periodic maintenance reduce this problem, but they inevitably affect throughput and productivity. QSight StayClean technology is designed to deliver high sensitivity and uptime for even the most challenging matrices. Due to a built-in hot-surface-induced desolvation (HSID) system, a continuous stream of hot gas is used as an acting self-cleaning agent, allowing the LC/MS/MS system to work with ‘dirty’ samples while maintaining the system free of contaminants. As a result, laboratories should be able to increase their throughput by simplifying sample extraction protocols and maintaining higher productivity with 35 more days of analysis per year.

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