Phenomenex Kinetex F5 pentafluorophenyl columns

Phenomenex announces Kinetex F5 - a robust pentafluorophenyl propyl (PFP) core-shell phase said to overcome the reproducibility and performance limitations of existing PFP and F5 products which were found to produce sporadic basic compound adsorption and analyte retention time shifting.

The phase is claimed to deliver improved reproducibility and reduced method development time with its dynamic and responsive chemical functionality. It is suitable for HPLC/UHPLC development work with its combination of polar and non-polar interactions including hydrogen bonding, electrostatic, hydrophobic, aromatic and steric/planar mechanisms. Additional versatility of the phase gives scientists the ability to use reversed phase, 2D-LC, HILIC, SFC or even 100% aqueous separation modes.

With its fluorinated groups and carbon ring structure, the product is suitable for both polar and non-polar compound separations as well as challenging methods that include halogenated, conjugated or isomeric compounds. It is available in 2.6 and 1.7 µm particle sizes and delivers all the advantages of Phenomenex Core-Shell Technology, including good resolution, high efficiency, easy method transferability and cost savings from reduced solvent consumption.

The Kinetex 2.6 µm F5 provides performance comparable to sub-2 µm particles on both standard HPLC and UHPLC systems. The 1.7 µm column delivers 20% greater efficiencies than fully porous sub-2 µm products.