Restek Raptor Polar X columns

Analysing polar compounds using liquid chromatography has historically been a challenge. Poor retention and peak shape, complex mobile phases that may not be MS-friendly, long equilibration times, low sensitivity and sample derivatisation are all complications that reduce lab efficiency and productivity.

Raptor Polar X columns from Restek are designed to retain and efficiently separate a broad range of polar analytes using a stationary phase that balances two retention mechanisms: HILIC and ion exchange. This hybrid phase is suitable for analysing acidic, basic and neutral polar compounds without time-consuming derivatisation or complex ion pairing, and it is especially compatible with mass spectrometry.

Easy changes to mobile phase conditions allow analysts to switch between modes and selectively tune retention for the compounds of interest without needing long equilibration times. The resolving power of the columns therefore helps to simplify the analysis of polar compounds.