The retinal pigment epithelium (RPE) comprises hexagonal cells organised into a monolayer that is densely packed with pigment granules. RPE cells play a critical role in visual function and photoreceptor viability.
Clonetics Human RPE cells are a useful tool in the study of age-related macular degeneration, retinistis pigmentosa and gene expression profiles of RPE.
Cryopreserved human primary RPE cells are packaged at passage 2 and contain ≥500,000 cells per vial.
Performance and quality-control testing includes: epithelial markers expression - ≥90%; pancytokeratin positive; fibroblast contamination - ≤10% positive cells; tight conjunction - ≥90%; endothelial marker (CD31) - ≤1% positive cells.
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