Enzo Life Sciences Recombinant Human Adiponectin

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Adiponectin controls many metabolic processes and is known to contribute to metabolic pathologies including diabetes, atherosclerosis and obesity. Obesity is primarily characterised by an excessive fat accumulation that may impair health. Adipose tissue contains differentiated cells called adipocytes that specialise in storing fat.

In addition to their function in controlling energy homeostasis, adipocytes release endocrine and paracrine signalling molecules called adipokines that are important in many physiological and metabolic processes. Some adipokines such as adiponectin, omentin, Nampt (Visfatin/PBEF), vaspin, resistin or RBP4 are involved in insulin signalling. Others regulate food intake and lipid metabolism (eg, leptin, chemerin).

Recent studies indicate high-molecular weight (HMW) adiponectin oligomers result in the most biologically active form of the protein. Recombinant Human Adiponectin from Enzo Life Sciences has been shown to have the following advantages: very high activity recombinant adiponectin; HMW and hexameric species mimic serum adiponectin in vitro: mammalian cell-derived protein guarantees proper post-translational modifications; high-purity protein ensures specificity.