AdipoGen animal-free recombinant monoclonal antibodies (RecMAbs)

AdipoGen develops recombinant monoclonal antibodies (RecMAbs) without the use of animals. The antibodies are created using an in vitro technology, antibody phage display — an alternative to the hybridoma technology that circumvents the limitations of the immune system. Antibodies developed by antibody phage display technology use human naïve antibody gene libraries.

There are many advantages to using RecMAbs recombinant antibodies instead of traditional antibodies, according to the company, including: no requirement of sacrificing animals in an animal facility; economical production and permanent storage of DNA clones; sequence-defined antibodies allowing reproducibility in experiments; and use of a single-chain antibody fragment to reconfigure a RecMAb into a full-length IgG construct for research purposes.