Biosensis Fluoro-Jade C (FJC) Powder for detecting neuronal degeneration

The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Tools for detecting neuronal degeneration are essential for identifying mechanisms of neurodegenerative diseases and potential treatments.

Fluoro-Jade C (FJC) from Biosensis stains all degenerating neurons regardless of specific insult or mechanism of cell death. The product exhibits a good signal-to-background ratio, as well as high resolution. This translates to a stain of high contrast and affinity for degenerating neurons, making it suitable for localising not only degenerating nerve cell bodies but also distal dendrites, axons and terminals.

The dye is resistant to fading and is compatible with virtually all histological processing and staining protocols. For large-scale studies, FJC Powder is useful for processing a large number of tissue sections. Detailed protocols are provided to ensure consistency and high-quality data.