Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway, where it helps convert glucose into energy. GAPDH also plays other roles in cells, such as helping regulate gene expression (transcription) and controlling cell death (apoptosis). In addition, changes in GAPDH localisation have been linked to neurodegenerative diseases, including Alzheimer’s and Huntington’s diseases.
Biosensis offers two types of GAPDH antibodies: a mouse monoclonal antibody (Cat #M-1376) and a rabbit polyclonal antibody (Cat #R-1701). These antibodies were specifically developed against highly purified pig GAPDH.
The antibodies have become a widely used tool in research because of their ability to detect GAPDH across multiple mammalian species, including humans, rats and mice, and multiple applications including western blotting, immunocytochemistry and immunohistochemistry, including paraffin-embedded tissues. They recognise an epitope within the peptide sequence corresponding to amino acids 254-273 of the human GAPDH protein, enabling detection and quantification in various experiments.
Phone: 02 9698 2022
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