CHROMagar C3GR supplement for detection of Gram-negative bacteria producing Beta-Lactamase

Friday, 19 September, 2014 | Supplied by: Dutec Diagnostics Pty Ltd



β-Lactamase production (ESBL, AmpC, etc) is the most common mechanism of β-lactam drug resistance in gram-negative bacteria. Many clinical laboratories currently screen for ESBLs but do not screen for AmpC β-lactamases, though bacteria (mostly Klebsiella pneumoniaE. coli, Enterobacter and Proteus) producing plasmid-mediated AmpC β-lactamases have been responsible for nosocomial outbreaks.

Therefore, it is crucial to ensure that proper surveillance is in place to help establish appropriate guidelines and policies for infection control. Rapid detection of bacteria producing these enzymes also allows for de-escalation to more targeted therapy to conserve carbapenem antibiotics for more serious infections.

The CHROMagar C3GR supplement added to CHROMagar Orientation contributes to the rapid screening of Gram-negative C3GR-producing bacteria. The supplement combines species colour differentiation and a selectivity that allows the growth of microorganisms with the reduced susceptibility to third-generation cephalosporins.

The supplement provides detection after overnight incubation and good species differentiation due to the chromogenic performances of supplemented CHROMagar Orientation. The product is composed of a powder-base CHROMagar Orientation and a supplement to enhance ESBL-producing bacteria.

It has high sensitivity, with the medium not inhibiting plasmid-mediated AmpC-producing bacteria. It also provides time and workload savings as, with direct culture available from the specimen, there is no need for a selective pre-enrichment.

Online: www.dutecdiagnostics.net.au
Phone: 02 9798 9066
Related Products

WPI Micro Fine Mesh Baskets

WPI has introduced a series of Micro Fine Mesh Baskets that are suitable for washing or...

AdipoGen animal-free recombinant monoclonal antibodies (RecMAbs)

AdipoGen develops recombinant monoclonal antibodies (RecMAbs) without the use of animals. The...

Larodan research-grade natural and synthetic phospholipids

Larodan develops a comprehensive range of research-grade lipids for use as analytical standards...


  • All content Copyright © 2019 Westwick-Farrow Pty Ltd