Clostridium difficile (C. difficile) is the causative agent of antibiotic-associated diarrhoea and pseudomembranous colitis. It produces two major exotoxins (toxin A and toxin B), which are the prototypes of the family of large clostridial cytotoxins. Some strains of C. difficile also produce a binary ADP-ribosylating toxin (CDT) which modifies actin. The pathogenic role of CDT binary toxin in diseases induced by C. difficile is not clear, but about 10% of strains isolated from patients with colitis contain CDT binary toxin genes.
List Labs manufactures highly purified native Clostridium difficile toxins: toxin A (TcdA) and toxin B (TcdB), for research use; TcdA is available lyophilised in buffer, whereas TcdB is available in a liquid formulation. They are distributed in Australia and New Zealand by Sapphire Bioscience.
Phone: 02 9698 2022
Norgen Biotek Bacterial EV Isolation Kit
The Bacterial EV Isolation Kit enables researchers to isolate extracellular vesicles directly...
Bertin Bioreagent Myelotracker kit for neutrophil detection
Bertin Bioreagent introduces Myelotracker, an innovative peptide-based probe specifically...
Amsbio CELLBANKER cryopreservation solutions
Each batch of Amsbio's CELLBANKER cryopreservation solution is manufactured under strict...
