Lumiprobe offers a series of DusQ fluorescence quenchers with different spectral properties and functional groups for oligonucleotide synthesis and other applications.
Dark quenchers are non-fluorescent chromophores that can absorb excitation energy from a fluorophore and dissipate it as heat. Quenchers are widely used to synthesise oligonucleotides: hydrolysable DNA probes, molecular beacons and scorpion primers. The use of quenchers in these applications has many advantages: low background fluorescence and good signal-to-noise ratio; high dynamic range; possibility of multiplexing since quenchers have no secondary fluorescence; and straightforward synthesis of DNA probes since quenchers are resistant to degradation at the deprotection stage.
Lumiprobe’s DusQ fluorescence quenchers are distributed in Australia and New Zealand by Sapphire Bioscience.
Phone: 02 9698 2022
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