TdB Labs polysaccharides

TdB Labs’ polysaccharide portfolio consists of both fluorescent and non-fluorescent polysaccharide derivatives. The company’s focus is dextran derivatives, but it also offers derivatives of other polysaccharides such as polysucrose, inulin, hyaluronic acid, trehalose and hydroxyethyl starch. These products are widely employed within the life science sector.

The fluorescent polysaccharides are mainly used for studies of permeability and microcirculation in cells and tissues, for studies of drug delivery, or as molecular size markers. The fluorescent products include derivatives labelled with FITC, TRITC, ATTO-dyes, and TdB Labs’ proprietary Antonia Red-dye.

The company’s non-fluorescent polysaccharides include dextran sulfates and charged polysaccharides with functional groups like carboxymethyl (CM), diethylaminoethyl (DEAE) and quaternary-ammonium (Q). Dextran sulfate sodium (DSS) has been used to induce colitis in mice and rats for more than 20 years. Dextran sulfates of lower molecular weights are often used as a cell media additive or as stabilisers. TdB Labs’ blue dextran is often used as a void volume marker in chromatography.