Protein interaction analysis

Bio-Rad Laboratories has released a GLH sensor chip for its ProteOn XPR36 protein interaction array system. The chip generates a high analyte signal through its high ligand activity and binding capacity. The amine coupling chemistry and polymer layer of the GLH sensor chip is similar to the ProteOn GLC and GLM chips, allowing ligand binding across a wide pH range.

The chip, consisting of a highly extended mixed polymer layer for maximum binding capacity, is designed for general amine coupling. It is optimised for protein-small molecule interactions as well as protein-protein interactions, where extremely high sensitivity is a primary concern. Beta testing has been successfully conducted in several customer laboratories in the US, Australia, Japan and Europe.