Thermo Scientific SOLAµ solid-phase extraction plates

Thermo Scientific SOLAµ solid-phase extraction (SPE) micro elution plates are designed to deliver robust, reproducible processing at elution volumes as low as 25 µL. The plates are claimed to improve sensitivity over comparable SPE products as much as 20-fold due to improved pre-concentration.

The SOLA macro-porous structure is designed for robust, reproducible results with consistent sample and solvent flow through the SPE stationary phase, which can mitigate blockages caused by viscous biological samples. The low elution volumes accommodated by SOLAµ plates can provide an efficient workflow by removing the blow-down stage of the SPE process. It offers the added benefit of more stability for molecules that are susceptible to adsorption and solvation issues.

The SOLAµ products are available in 96-well-plate format and include: HRP (reverse phase); SCX (mixed-mode strong cation exchange); SAX (mixed-mode strong anion exchange); WCX (mixed-mode weak cation exchange); and WAX (mixed-mode weak anion exchange) stationary phases.

The plates combine polyethylene frit materials and stationary phase materials into a uniform stationary phase. This mitigates problems caused by voiding, channelling and packing inconsistencies, which can cause variability in results. The design is said to enhance reproducibility - well to well, plate to plate and batch to batch.