Millennium Science cAMP Alphascreen application note
25 May, 2011 | Millennium Science Pty Ltd
Adenosine 3′, 5′ cyclic monophosphate (cAMP) plays a critical role in the transmission of signals by functioning as a ‘second messenger’. Binding of hormones or ligands to their respective receptors can either inhibit or enhance the production of cAMP by changing the activity of the enzyme adenylate cyclase. Adenylate cyclase is a membrane-associated enzyme that catalyses the formation of cAMP from ATP. Intracellular cAMP levels, in turn, regulate enzymatic activity of numerous protein kinases, which phosphorylate specific targets setting off a cascade of cellular events. Because of the importance of cAMP as a cellular messenger, several different reading methodologies have been developed to measure cellular levels, one of which is AlphaScreen. Here we describe and demonstrate the ability of the Synergy 2 to quantitate cAMP using this methodology.
Epoch multi-volume nucleic acid quantification application note
25 May, 2011 | Millennium Science Pty Ltd
Nucleic acids isolated from a variety of sample types such as animal models, body fluids or eukaryotic and bacterial cells provide the starting material for a broad range of downstream applications including gene expression, genotyping, sequencing and cloning. Quantification of isolated nucleic acid is necessary prior to introduction into these applications. The Epoch Spectrophotometer System provides a means of obtaining accurate measurement over a wide range of sample concentrations and volumes, including microvolume quantification. Comparison to other microvolume dedicated devices, such as NanoDrop, shows equivalent performance.
Hamilton Microlab 600 syringe pump
19 May, 2011 | Grace Discovery Sciences
The Hamilton Microlab 600 is a precise syringe pump with a graphical user interface designed to quickly and easily dilute and dispense liquids from 100 nL to 50 mL.
Air Science ductless metal-free hybrid Class 2 laminar flow cabinet
02 May, 2011 | LAF Technologies Pty Ltd
The Air Science ductless metal-free hybrid Class 2 laminar flow cabinet can be used in laboratories where both process and operator protection is required in a metal-free or corrosive environment.
Lonza Platinum UltraPak Bioprocess single-use containers
21 April, 2011 | Capsugel Australia Pty Ltd
The Platinum UltraPak Bioprocess single-use containers can be used for packaging of cell culture media, reagents and buffers as well as containment and storage vessels for final product yielded from downstream manufacturing processes.
Odyssey Thera compounding profiling service
20 April, 2011 | Capsugel Australia Pty Ltd
Using cutting-edge Protein-fragment Complementation Assay technology from Odyssey Thera, Lonza is able to offer profiling services that can shape and influence critical decisions about drug candidates.
BOC Gases L40 panel-mounted point-of-use regulator
20 April, 2011 | BOC Limited
The L40 panel-mounted regulator, part of the HiQ Redline range, can be used to meet the purity and safety demands required by specialty gases. Together with the gas panel, the regulator maintains a stable outlet pressure at the workstation and can be used in a wide variety of laboratories and applications.
Erlab Captair Molecode S automated recirculating fume cabinet filter alarm system
20 April, 2011 | Gallay Medical & Scientific Pty Ltd
The Erlab Captair Molecode S automated recirculating fume cabinet filter alarm system can be used for laboratory managers working with strong substances who require the assurance that their fume cabinet is keeping the workplace safe.
Schott Duran GL 25 and GL 45 premium caps
20 April, 2011 | SCHOTT Australia Pty Ltd
Designed to fit on all Schott Duran laboratory bottles, the GL 25 and GL 45 premium caps are made from TpCh260 with a PTFE coated silicone seal.
Life Technologies BigDye Direct Cycle Sequencing Kit
20 April, 2011 | Applied Biosystems Pty Ltd
Life Technologies has announced an advancement in capillary electrophoresis (CE) sequencing reagents that simplifies the Sanger sequencing workflow by combining post-PCR clean-up and cycle sequencing into a single step and allows reads as close as one base from the primer using POP-7 polymer.
Innova Biosciences imm-Link Immunogen Linking Kits
20 April, 2011 | BioNovus Life Sciences
Innova Biosciences imm-Link Immunogen Linking Kits simplify the conjugation of haptens to carrier proteins. Large immune responses are stimulated by BSA, ovalbumin and keyhole limpet hemocyanin (KLH) and are typically used as carrier proteins to generate antibodies against small antigens (eg, peptides or organic compounds - ie the ‘hapten’). To successfully stimulate the production of antibodies, the antigen needs to be covalently linked to a carrier protein.
Oxford Expression Technologies baculoFECTIN transfection reagent
19 April, 2011 | BioNovus Life Sciences
Oxford Expression Technologies has launched baculoFECTIN, a non-toxic transfection reagent optimised for use in insect cells and proven to produce greater levels of transfection - leading to high-level protein expression.
Gilson PLC 2020 personal liquid chromatography system
19 April, 2011 | John Morris Scientific Pty Ltd
Gilson has developed a ‘personal’ liquid chromatography system, the PLC 2020, designed to support individuals or small groups of chemists. The system is suitable for normal/reverse phase HPLC and flash purification applications.
Lonza Nucleofector human melanocytes kits and Amaxa protocols
19 April, 2011 | Capsugel Australia Pty Ltd
Various Nucleofector Kits and corresponding Amaxa optimised protocols are available for the transfection of human melanocytes using the different Nucleofection platforms.
Carl Zeiss Intermediate LED tubes S
19 April, 2011 | ZEISS Group
The Carl Zeiss Intermediate LED tubes S offer very good fluorescence homogeneity in a large stereo field. The fluorescence brightness and high contrast make them suitable for routine dissections of marked model organisms or for the screening of dyed cell cultures.
