Gene therapy trial results in significant vision improvements
17 September, 2024The vision of people with a rare inherited condition that causes them to lose much of their sight early in childhood was anywhere from 100 to 10,000 times better after they received gene therapy.
Non-hormonal drug treats hot flashes in menopausal women
06 September, 2024The investigational drug elinzanetant has been found to reduce the frequency and severity of hot flashes associated with menopause while improving women's sleep and quality of life.
Children's heart implant expands when activated by light
29 August, 2024Researchers have designed a shunt that expands when activated by light, which could reduce the number of open-chest surgeries required by children with congenital heart defects.
Malaria parasites tricked into ingesting drugs
28 August, 2024Scientists have developed a 'Trojan horse' method that tricks malaria parasites into ingesting a fatal dose of drugs by exploiting the parasite's need for cholesterol to survive.
Two-step flu vaccine strategy shows promise in pigs
22 August, 2024A two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs.
Improving autoimmune conditions in Down syndrome patients
21 August, 2024A first-in-kind clinical trial has tested the safety and efficacy of a JAK inhibitor in decreasing the burden of autoimmune skin conditions in people with Down syndrome.
Iron-binding drug could be used to treat ovarian cancer
20 August, 2024Iron is essential for multiple cellular processes, so actively multiplying cancer cells often need larger amounts of it than normal cells.
First-in-human implantation of BiVACOR's total artificial heart
30 July, 2024The first-in-human implantation was performed in a critically ill 57-year-old man who was in cardiogenic shock and awaiting a heart transplant.
Sodium ascorbate rapidly reverses sepsis-induced brain injury
23 July, 2024A megadose of sodium ascorbate can turn around sepsis-induced low oxygen levels, low blood flow and high temperature within the brain's frontal cortex.
New MDMA variants could enable safe psychotherapeutic use
11 July, 2024The newly developed MDMA variants have been modified in such a way that the positive effects are retained and the negative effects are reduced.
Treating rare skin diseases with transplants
05 July, 2024Researchers at Nagoya University have treated the skin diseases epidermolytic ichthyosis (EI) and ichthyosis with confetti (IWC) by transplanting genetically healthy skin to inflamed areas.
New therapy could treat hypertension-induced organ damage
28 June, 2024Compound17b (Cmpd17b) is a potent therapeutic agent capable of safeguarding against the ravages of high blood pressure on vital organs.
Nanoparticle could help map, treat children's brain cancer
26 June, 2024The nanoparticle could be used for delivering small interfering RNA (siRNA) directly to the brain cancer site, slowing tumour growth without causing signs of toxicity.
Nanodroplet drug carriers triggered by ultrasound
24 June, 2024By releasing the drug at exactly the desired spot in the body, this allows the total dose to be dramatically lower, which should minimise side effects.
Drug trial results show lung cancer patients are living longer
21 June, 2024Five years after treatment, 60% of patients treated with lorlatinib remained alive and without disease progression; this compared to just 8% for patients who received crizotinib.
