Click chemistry is not a specific reaction but rather chemistry tailored to generate substances quickly and reliably by joining small units together. It is meant to mimic nature which also generates substances by joining small modular units (eg, amino acids into proteins). But precisely how it works had been unclear since its invention at The Scripps Research Institute (TSRI) more than a decade ago.
It looks like the particle discovered at the Large Hadron Collider last year is an elusive Higgs boson but whether this is the Higgs boson of the Standard Model of particle physics, or possibly the lightest of several bosons predicted in some theories that go beyond the Standard Model, has yet to be established.
On 4 February 2013, the University of Leicester announced it had discovered the remains of the last Plantagenet king, King Richard III, who died in 1485.There was strong circumstantial evidence that a skeleton found at the site of the Grey Friars church in Leicester was indeed that of King Richard III. However, before the identity of the skeleton could be confirmed, rigorous scientific investigations including DNA analysis, radiocarbon dating and skeletal examination were required.
Researchers have discovered a new compound that restores the health of mice infected with methicillin-resistant Staphylococcus aureus (MRSA), an otherwise dangerous bacterial infection.
Scientists at The Scripps Research Institute (TSRI) have achieved a feat in synthetic chemistry by inventing a scalable method to make complex natural compounds - polyhydroxylated steroids. These compounds, used in heart-failure medications and other drugs, have been notoriously problematic to synthesise in the laboratory.
Trasis has extended its range of molecules to 18F-L-Dopa with a reliable nucleophilic method, making this compound easy and safe to produce.
The CLF10 sc analyser is an amperometric analyser which leverages Hach’s self-diagnostics to alert users whenever the process has changed or the instrument needs servicing.
An automated segmented flow analyser, the AA3 from Seal Analytical, is being used at BASF’s manufacturing facility at Ludwigshafen in Germany to protect manufacturing equipment from corrosion or chemical attack from potential impurities in demineralised water, boiler feed water and steam condensate.
Scientists at The Scripps Research Institute have shown how to synthesise in the laboratory an important set of natural compounds known as terpenes. The largest class of chemicals made by living organisms, terpenes are made within cells by some of the most complex chemical reactions found in biology.
An enzyme in the bacterium that causes potato scab could help create new, environmentally benign biocatalysts with the potential to cut use of the highly corrosive chemical nitric acid.
The latest sensor design of Michell Instruments’ S8000 Remote chilled mirror hygrometer combines high-accuracy temperature control with new materials to improve reliability and avoid condensation.
Ziltek and CSIRO have announced the commercialisation of a handheld device for the rapid in-field analysis of petroleum contamination in soil. The RemScan device uses an infrared signal to directly measure petroleum hydrocarbons in soil.
Scientists at The Scripps Research Institute have developed a powerful new technique for manipulating the building-block molecules of organic chemistry. The technique enables chemists to add functional molecules to previously hard-to-reach positions on existing compounds, making it easier for them to generate new drugs and other organic chemicals.
The speed of hydrogenation and hydrogenolysis reactions has been found to increase in the presence of water. Researchers found that the presence of even the most minute amounts of water - on the order of those in an outer-space vacuum - can accelerate the diffusion of hydrogen atoms on iron oxide by 16 orders of magnitude at room temperature.
Spectro has released a range of analytically significant technology platforms in the field of oil and lubricant analysis. The company’s lab, field-portable and handheld analytical tools are based on emission, infrared, FTIR and X-ray technologies, among others.