As a tool, conventional mass spectrometry is a good method for differentiating between proteins with different masses. However, as different folded forms of a particular protein have identical masses, it is virtually impossible to differentiate them by conventional means. That's where the Waters Synapt HDMS system and its embedded ion mobility technology can help.
Dietary fibre including cellulose, hemicelluloses, lignin, pectin, rubbers and waxes can be determined by digestion with thermostable enzymes in foods and animal feeds. AOAC International (Official Methods of Analysis) has proposed enzymatic method 985.29.
Physicists at NIST-Boulder have carried out a powerful new spectroscopic study of a gas sample using optical frequency combs.
Thermo Fisher Scientific has been awarded a US Patent on Spectrometric Data Cleansing. This patent describes a method for filtering artefacts from Raman spectra and is of particular use in removing the distorted data points generated by cosmic ray interference. Elimination of spectral artefacts facilitates automated analysis by such methods as reference library searches and correlation with standard spectra.
Researchers have solved the structure of a DNA-protein complex that is crucial in the spread of antibiotic resistance among bacteria, providing insights into how cells successfully divide into two new cells with intact DNA.
US scientists have modelled an enzyme critical to the process of DNA transcription and replication which could be a prime target for antibacterial and anticancer drugs.
Thermo Fisher Scientific has introduced a line of silica-based TurboFlow columns designed exclusively for use with Thermo Scientific Transcend Systems. The columns provide scientists in clinical research and pharmaceutical analysis the capability to integrate online sample preparation with LC-MS analysis. The TurboFlow XL columns enable researchers to reduce sample preparation time and minimise ion suppression, while providing faster analysis and more confident data.
Australia has long been known for developing leading-edge scientific instrumentation and this reputation is set to continue with the development of an impedance spectrometer that is up to 1000 times more accurate than its competitors
Conventional wide field fluorescent imaging is hindered by the detection of out of focus light above and below the specimen plane being examined. This has limited traditional fluorescent microscopes to a Z-direction resolution of approximately 1 µm. This limitation has spurred the adoption of the laser scanning microscope (LSM) into examination of subcellular biology with the capability of Z-resolutions below 0.5 µm.
The Centenary Institute, one of Australia ’s leading medical research institutes, has unveiled a microscope more powerful than any other in the country.
The AES Chemunex Labguard2 is a wireless system that continuously monitors laboratory equipment and automatically alerts users to any problems. Easy to use and install, the Labguard2 provides the data required for FDA CFR21 part 11 and GLP compliance.
The UVP PhotoDoc-It imaging system is suitable for basic documentation of gels and plates. The system is configured for limited laboratory space and budgets.
Scientists in Spain have found a way to recycle CDs, DVDs and disc players as portable substance analysers.