Sigma Life Science CompoZr Knockout ZFN extended range
17 October, 2011 bySigma Life Science has announced a further development of its CompoZr zinc finger nuclease (ZFN) technology with the release of its Knockout ZFNs covering the entire genomes of both mice and rats. The expansion of the Knockout ZFNs for every mouse and rat gene is in its initial phase, which complements the existing range of Knockout ZFNs for the entire human genome.
Nanopore sequencing licensed for rapid DNA sequencing
13 October, 2011Roche and Arizona Technology Enterprises (AzTE) have agreed to license several technologies to develop a new DNA sequencing system.
How you read the gene alters what you get
15 July, 2011Multiple varients of a given gene can be made with the same genetic instructions, it just depends on how the cell ‘reads’ the DNA. Alternative versions of mRNA transcripts can be achieved mainly by altering the start and end reading of a gene and this seems to be more common than the traditionally expected alternative, splicing.
Genetic testing for IVF embryos
06 July, 2011 byCouples affected by carriers of genetic diseases may benefit from a new technique which helps ensure that in vitro fertilised babies are free of both the disease in question and other chromosomal abnormalities.
Social relationships and genomics
06 July, 2011 byScientists supported by Genome BC have set a new standard for studying outbreaks of infectious disease by combining advanced genomics with a detailed map of the social relationships between cases to investigate a recent outbreak of tuberculosis in a BC community.
Microarray technology speeds up drug development
06 July, 2011 byRNA interference technology, which is used in cell biology, has revolutionised functional research of gene products in the last ten years.
Is the genomics bubble sustainable?
06 July, 2011 byIn the ten years since the human genetic code was mapped, expectations among scientists, the healthcare industry, policymakers and the public have remained high concerning the promise of genomics research for improving health.
Integrated DNA Technologies RNA interference (RNAi) products
20 June, 2011 byIntegrated DNA Technologies (IDT) has a comprehensive range of customisable products for RNA interference (RNAi) applications. The Screening Dicer-substrate siRNA (DsiRNA) provides researchers with a quick solution for their RNAi requirements. IDT’s DsiRNAs are chemically synthesised 27-mer RNA duplexes optimised for Dicer processing and incorporation into the RISC complex, resulting in an increase in potency. IDT’s predesigned library includes over 3,000,000 DsiRNAs designed against human, mouse, rat, cow, dog, chicken and chimp transcriptomes within RefSeq, enabling the production of DsiRNAs to meet the majority of user requirements.
Single molecule sequencer
16 June, 2011A gene expression technique adapted for single molecule sequencing has enabled researchers at the Riken Omics Science Center (OSC) to accurately and quantitatively measure gene expression levels using only 100 ng of total RNA. The technique, which pairs Riken’s Cap Analysis of Gene Expression (CAGE) protocol with the Helicos Genetic Analysis System opens the door to the detailed analysis of gene expression networks and rare cell populations.
Easy-to-use genome analyser offered
14 June, 2011Scientists have developed a genome analyser and browser that allows biologists to analyse and process high-throughput data.
Norway harvests genomic expertise
10 June, 2011Norway is cooperating with Canada and Chile to sequence the salmon genome. The knowledge generated could provide the answers to several problematic issues involving Norwegian farmed salmon - and lead to major competitive advantages for companies taking part in the project.
Beckman Coulter GenomeLab GeXP Genetic Analysis System
25 May, 2011The GenomeLab GeXP Genetic Analysis System can be used to multiplex up to 30 genes in one reaction, quantitatively and reproducibly, using only a small amount of RNA sample.
Do these genes make my backside look big?
05 May, 2011An intriguing example of epigenetics is evident in the size of the backside of ‘callipyge’ sheep – leading to the genuine question: do these genes make my backside look big?
Sigma Life Science and Cofactor Genomics rat genome database
15 April, 2011 bySigma Life Science’s SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyse sequence data using next-generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.
Beckman Coulter SPRIworks Fragment Library System III
13 April, 2011 bySPRIworks Fragment Library System III automates the preparation of libraries for the Life Technologies SOLiD Sequencer. With the introduction of this third system in a series, researchers can use the SPRIworks system to automate library preparation for the three major next-generation sequencing platforms.
