Sage-N Research signs microbial identification agreement
06 June, 2011
Sage-N Research has signed an exclusive agreement with the US Army Edgewood Chemical Biological Center (ECBC) to license technology for microbial identification.
The great cell race
01 June, 2011
Have you got the world’s fastest cell? Now, for the first time in history, you can race your cells in an international competition. If they win it will be by less than a hair’s breadth as the entire track length is only a hair’s breadth - 100 µm.
Gilson Trackman portable light box
31 May, 2011 | Supplied by: John Morris Scientific Pty Ltd
The Gilson Trackman portable light box can be used to keep track as users pipette from one microplate to another. The tool is claimed to simplify laboratory work, improve productivity and reduce pipetting errors and cross-contamination.
TTP LabTech Libra2 acoustic biosensor
31 May, 2011
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Supplied by:
Millennium Science Pty Ltd
TTP LabTech’s acoustic biosensor, Libra2, can be used for the study of glycosylation patterns on cell membranes.
BioTek cytokines ELx405 washer application note
25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biorad_cytokine_app_note-2010.pdf
Cytokines and growth factors are cell signalling proteins that mediate a number of physiological responses. In addition, they are also associated with a number of diseases including tumour growth and metastasis, infections and inflammation. Because these molecules rarely act unilaterally it is important to assess a number of them in parallel. The advent of multiplex assays using Luminex xMAP bead technology has simplified the task of performing multiple assays on samples. BioTek has demonstrated how to automate the wash steps of the Bio-Rad HumanCytokine 8-plex assay kit using the ELx405 Magnetic Bead Washer.
Millennium Science cAMP Alphascreen application note
25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/camp_alphascreen_assay-2010.pdf
Adenosine 3′, 5′ cyclic monophosphate (cAMP) plays a critical role in the transmission of signals by functioning as a ‘second messenger’. Binding of hormones or ligands to their respective receptors can either inhibit or enhance the production of cAMP by changing the activity of the enzyme adenylate cyclase. Adenylate cyclase is a membrane-associated enzyme that catalyses the formation of cAMP from ATP. Intracellular cAMP levels, in turn, regulate enzymatic activity of numerous protein kinases, which phosphorylate specific targets setting off a cascade of cellular events. Because of the importance of cAMP as a cellular messenger, several different reading methodologies have been developed to measure cellular levels, one of which is AlphaScreen. Here we describe and demonstrate the ability of the Synergy 2 to quantitate cAMP using this methodology.
BioTek HTRF AKT application note
25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biotek-htrf-akt_app_note_automated-2011.pdf
AKT is a serine/threonine protein kinase that plays a key role in cellular processes. AKT has become a popular target for drug discovery campaigns, due to the fact that AKT inhibitors may help to treat a number of cancers. BioTek has demonstrated an automated homogeneous assay to probe AKT phosphorylation at its serine 473 residue using endogenous levels of kinase expression within human primary HUVEC cells.
Epoch multi-volume nucleic acid quantification application note
25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/multi-volume_analysis_app_notefinal-2011.pdf
Nucleic acids isolated from a variety of sample types such as animal models, body fluids or eukaryotic and bacterial cells provide the starting material for a broad range of downstream applications including gene expression, genotyping, sequencing and cloning. Quantification of isolated nucleic acid is necessary prior to introduction into these applications. The Epoch Spectrophotometer System provides a means of obtaining accurate measurement over a wide range of sample concentrations and volumes, including microvolume quantification. Comparison to other microvolume dedicated devices, such as NanoDrop, shows equivalent performance.
Non-invasive ‘point of care’ haemoglobin monitoring coming closer
05 May, 2011
’Point of care’ monitoring of haemoglobin levels is nearing reality in operating rooms as a spectrophotometric haemoglobin sensor is providing a new approach to non-invasive monitoring of blood haemoglobin levels during surgery.
Do these genes make my backside look big?
05 May, 2011
An intriguing example of epigenetics is evident in the size of the backside of ‘callipyge’ sheep – leading to the genuine question: do these genes make my backside look big?
Life Technologies BigDye Direct Cycle Sequencing Kit
20 April, 2011 | Supplied by: Applied Biosystems Pty Ltd
Life Technologies has announced an advancement in capillary electrophoresis (CE) sequencing reagents that simplifies the Sanger sequencing workflow by combining post-PCR clean-up and cycle sequencing into a single step and allows reads as close as one base from the primer using POP-7 polymer.
Innova Biosciences imm-Link Immunogen Linking Kits
20 April, 2011 | Supplied by: BioNovus Life Sciences
Innova Biosciences imm-Link Immunogen Linking Kits simplify the conjugation of haptens to carrier proteins. Large immune responses are stimulated by BSA, ovalbumin and keyhole limpet hemocyanin (KLH) and are typically used as carrier proteins to generate antibodies against small antigens (eg, peptides or organic compounds - ie the ‘hapten’). To successfully stimulate the production of antibodies, the antigen needs to be covalently linked to a carrier protein.
Integrated DNA Technologies PrimeTime Pre-designed qPCR Assays
18 April, 2011 | Supplied by: Integrated DNA Technologies
PrimeTime Pre-designed qPCR Assays work for human, mouse and rat transcriptomes. Users can search and select from the online database that contains thousands of assays. All assays are designed to span exons, protect against non-specific amplifications, avoid known SNPs and minimise the impact of secondary structure. Consisting of two primers and a hydrolysis probe, all three components are shipped in a single tube and are claimed to provide \>90% efficiency.
Qiagen Investigator Quantiplex Kit
16 April, 2011 | Supplied by: QIAGEN Pty Ltd
The Investigator Quantiplex Kit has been designed to quickly confirm that forensic DNA samples contain sufficient DNA for genetic fingerprinting analysis. The kit quantifies the human DNA in the sample and establishes whether it contains inhibitors that may interfere with downstream applications.
Sigma Life Science and Cofactor Genomics rat genome database
15 April, 2011 | Supplied by: Merck
Sigma Life Science’s SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyse sequence data using next-generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.
