White Papers/Resources

Monitoring with mean kinetic temperature in GxP environments

Regulatory bodies in drug manufacturing and distribution have long been working together to create standards for temperature monitoring that will ensure the quality of drugs, devices and biotechnology. The mean kinetic temperature (MKT) value has been identified as a potential tool for evaluating the impact of temperature on product quality.

The solution for a seamless quantitative bioanalysis

High selectivity is a critical element of successful quantitative bioanalysis. Recent technology advances have increased selectivity well beyond its previous gold standard — providing bioanalytical scientists with new dimensions and tools with which to work.

Continuous environmental monitoring — compliance and best practice tips

Automated environmental monitoring systems are now a critical element in many laboratory operations. To reduce your risk of adulterated product and missing data, ongoing system maintenance is essential. This is easily achieved by integrating the software-based system into your own organisation's quality system.

Protective solutions for glove allergies

Wearing glove products can cause adverse skin reactions, ranging from irritant contact dermatitis to severe allergic responses such as anaphylaxis.

The ultimate guide to hand protection in life sciences

Hand protection is rarely a one size fits all, especially in the life sciences. Whether hands need to be protected from hazards or products require a complete barrier, hand protection requires careful selection.

Advantages of Wavelength Scanning in Fluorescence and Absorbance Assays

EnVision® Multilabel Plate Reader, widely used in biological assay studies across the field and available in a number of configurations, incorporates monochromator technology in its two options. Absorbance Monochromator option is capable of performing absorbance assays while Fluorescence Intensity Monochromator option can be used for both absorbance and fluorescence intensity assays (quad monochromator design).

Gene expression and miRNA data analysis

Automated analytical pipelines that are modular and flexible, combined with the use of standardised file formats, can facilitate miRNA and whole transcriptome data analyses. This white paper discusses methods and bioinformatics tools that can be logically connected to create such automated pipelines from raw sequences to statistical reporting and mapped counts assigned to each gene or miRNA.

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Flow cytometric chromosome classification

Flow cytometric chromosome classification has been routinely used in the analysis of mammalian karyotypes as well as to assess chromosomal abnormalities. Download this tech paper for more information on how highly purified fractions of chromosomes can be isolated rapidly from the labelled chromosomes using a cell sorter.

Assessing yeast viability

Microorganisms such as yeast are used in many biotechnology applications including genetic engineering, vaccine development and the production of food. This Tech Paper presents an accurate and rapid method for assessing the viability of yeast using a flow cytometric approach.

Assessing bacterial viability

Assessment of bacterial viability is crucial to many applications ranging from the production of food and medicine to environmental monitoring.

Download this Tech Paper to learn about an assessment approach using flow cytometric analysis.

DNA/RNA extraction from formalin fixed paraffin embedded tissue samples

To find out about an automation-friendly process for extracting total nucleic acid from formalin-fixed, paraffin-embedded tissue samples, download this tech paper.

Genomic DNA: extraction from whole blood

To find out how a DNA purification system isolates and purifies genomic DNA (gDNA) from whole blood, serum and FTA cards, download this tech paper.