Life Scientist > Molecular Biology

Late-life exercise shows rejuvenating effects in mice

27 January, 2022

US researchers have found that exercise may quite literally be helping us to stay young — on an epigenetic level, that is.

Scientists uncover antibiotic-resistance gene in E. coli

27 January, 2022

Researchers found that a particular form of E. coli had a previously unnoticed gene that made it highly resistant to commonly prescribed antibiotics.

Antibiotic-resistance gene 'jumped' to dangerous pathogen

18 January, 2022

Until now, it was believed that the Adelaide Imipenemase (AIM-1) gene was only found in the South Australian capital city.

Coronary heart disease triggered by complex networks of genes

17 January, 2022

The findings could make it easier to screen for the disease, which is caused by thousands of genes that interact with other risk factors like smoking.

Using CRISPR and transposons for CAR T cell production

21 December, 2021 by Marwan Alsarraj*, Biopharma Segment Manager, Digital Biology Group

CAR T cells are most often manufactured using viruses, but new research is exploring the benefits of using alternative gene editing systems for this purpose.

Found: a genetic link to non-alcoholic steatohepatitis

10 December, 2021

Researchers found that albino mice with a point mutation in the tyrosinase gene are more susceptible to NASH than mice carrying the non-mutated gene.

Gene editing used to create single-sex litters of mice

09 December, 2021

UK scientists have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.

CRISPR gene editing can favour cells with cancer-linked mutations

22 November, 2021

The findings point to a need for caution in the use of CRISPR-based gene therapies.

Genetic risk factors identified for spine osteoarthritis

17 November, 2021

HKU researchers helped identify that the SOX5 gene, which is known to be essential for the development of the intervertebral discs, is implicated in spine OA.

So-called 'dust specks' are actually genome building blocks

09 November, 2021

Tiny 'microchromosomes' in birds and reptiles are linked to a spineless, fish-like ancestor that lived 684 million years ago.

Mapping the epigenetic signatures of pain

20 October, 2021

Scientists carried out a complete epigenomic study to define specific biomarkers for each type of pain, in order to be able to categorise the various types of pain quickly.

A single gene helps regulate the sleep–wake cycle

12 October, 2021

Using the genetic model organism Drosophila melanogaster, researchers discovered that the Nf1 gene is essential for the regulation of the sleep–wake cycle.

Genetic trigger for type 1 diabetes may be in the lungs

17 September, 2021

New research supports a theory that respiratory viral infections can trigger the onset of type 1 diabetes.

New regulatory regions uncovered on the human genome

07 September, 2021

By analysing genomic data from more than 30,000 people, researchers revealed thousands of new regulatory regions that control disease-linked genes.

Identifying genetic causes of childhood epilepsy

02 September, 2021

Genetic testing is crucial in epilepsy patients in order for them to receive appropriate counselling and treatment.

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